Services for CRO

Synthesize compounds for SAR studies

Develop synthesis for complex molecules

Synthesize common intermediates on a larger scale

Synthesize impurities

Scale up to kilogram scale

Provide Suli’s catalog building blocks

Services for CDMO

Deliver products

Scale up to kilogram scale

Develop process and scale up from pilot to commercial scale

Synthesize compounds for SAR studies

Synthesize impurities

Deliver know-how

Optimize the existing synthesis

Develop new and economical synthesis for targeting compound

Develop analytic method

Deliver reports and CMC documents

Always provide reports for all CDMO projects

Provide CMC documents/tech pack for registration purpose

Suli

Technical Expertise

High pressure reaction (hydrogenation)

The company has a total of 19 hydrogenation reactors, made of SS and Hastelloy alloy materials, which can meet different reaction conditions, with a maximum pressure of~10MPa

Independently developed technology platform and catalog products for asymmetric hydrogenation synthesis of chiral amines and chiral alcohols

Fluorination and bromination reactions

The company is equipped with one Hastelloy alloy reactor, which can be used for fluorination and bromination reaction production

Rich experience in bromine operation, including bromine procurement, transportation, post-treatment, bromine recovery, etc

Rich experience in the production of fluorination reagents, such as DAST, BAST, TMAF, and selective fluorination

Low temperature and cryogenic reaction

The company is equipped with a low-temperature reactor, cooled by liquid nitrogen, and the temperature can reach -78 ℃

Rich experience in Grignard reaction production, such as using n-BuLi, iPrMgCl, LDA, LiHMDS, DIBALH, etc

Enzyme catalyzed reaction

The company has rich experience in enzyme screening process research and development;

Rich experience in enzyme catalyzed reaction production scaling up

Isotope compounds

Has extensive experience in operating isotopes C13 and deuterated compounds, including detection, research and development, production, procurement, export, etc

Suli